788 N Jefferson St # 880, Milwaukee, WI 53202
Modern Dentistry
ABOUT US
At Smile MKE, we believe a healthy smile changes everything.
OUR HISTORY
Modern Dentistry with a Personal Touch
Smile MKE offers modern, personalized dental care in the heart of downtown Milwaukee. From exams, cleanings, and restorative care to dental emergencies, whitening, Botox, TMJ and facial pain treatment, sedation dentistry, and care for patients with special needs, every visit is centered around you. Enjoy advanced technology and attentive care in an elegant boutique setting overlooking Cathedral Square and the Milwaukee skyline. Conveniently located for those who live and work downtown, Smile MKE accepts most private dental insurance plans. Part of Major Dental Clinics, Smile MKE combines trusted expertise with a fresh, modern approach to everyday dental care.
ABOUT US
FOUNDED ON A PASSION
for providing extraordinary care, Smile MKE was created to offer patients a truly elevated dental experience. Our practice blends clinical excellence, advanced technology, and a warm, patient centered philosophy to help you achieve a healthy, confident smile that lasts a lifetime.
COMPASSIONATE CARE
We listen, we care, and we treat you like our family.
CLINICAL EXCELLENCE
Experience, proven techniques, outstanding results.
BEAUTIFUL SMILES
Precision treatments designed for health, function, and beauty.
LASTING RELATIONSHIP
We’re here for your smile today and for years to come.
MEET OUR SMILE MKE DOCTORS
our wonderful doctors are here to make every visit comfortable, personalized, and positive!
OUR DOCTORS
AGNES DOMAGALA, DDS
Dr. Agnes Domagala brings more than two decades of experience to Smile MKE, combining advanced clinical care, academic leadership, and a warm, patient-centered approach. She is an Associate Professor at Marquette University School of Dentistry and previously directed its Dental Emergency and Special Care Clinics for 15 years.
Her clinical interests include preventive and restorative dentistry, dental emergencies, TMJ and facial pain, Botox therapy, conscious sedation, and care for patients with complex medical needs, disabilities, or dental anxiety.
Dr. Domagala graduated from the Medical University of Silesia in Poland and completed a General Practice Residency and Postgraduate Fellowship at Marquette. Her honors include induction into Omicron Kappa Upsilon, Milwaukee Magazine’s Woman of Distinction recognition, and the 2026 Outstanding Pole in the USA in Science.
Outside dentistry, she enjoys sailing, cooking, traveling, and spending time with friends and family.
"My goal has never been to simply fix teeth. It's to care for the whole person—helping them smile, live, and feel better every day."
— Dr. Agnes Domagala
OUR DOCTORS
EKTA DESAI, DDS
Dr. Ekta Desai is a general dentist who is passionate about providing thoughtful, comprehensive care and helping her patients achieve healthy, confident smiles. She earned both her undergraduate degree and Doctor of Dental Surgery degree from Marquette University, graduating from Marquette University School of Dentistry in 2016.
Dr. Desai is deeply committed to lifelong learning and continuing education. She has completed the curriculum at the renowned Kois Center in Seattle, where she received advanced training in comprehensive, evidence-based dentistry.
Outside of the dental office, Dr. Desai loves reading, traveling, and exploring new places and experiences. She is also passionate about comedy and performs both improv and stand-up.
“I want every patient to feel heard, comfortable, and confident in their care. My goal is to understand what matters to you and create a thoughtful plan for a healthy, confident smile.”
— Dr. Ekta Desai
OUR DOCTORS
NIKI CHAGANI, DDS
Dr. Chagani believes that optimal dental care results from a good dentist and patient relationship, one which is centered around excellent communication. Her mission is to provide excellent care to her patients, focusing on prevention and encouraging healthy smiles. She firmly believes in a conservative treatment philosophy that emphasizes patient comfort and long-term welfare.
As such, she treats the whole person, not just teeth. Dr. Chagani went to school at Boston University and graduated Cum Laude. She also completed and Advanced Education in General Dentistry at Marquette University.
While dentistry and service are Dr. Chagani’s passions, she enjoys spending time with family and friends, and traveling.
“I believe the best dental care begins with trust and open communication. My goal is to provide conservative, preventive care that keeps patients comfortable and supports healthy smiles for years to come, while always treating the whole person, not just their teeth.”
— Dr. Niki Chagani
OUR DOCTORS
DANIEL DOMAGALA, DDS, MS
Dr. Daniel Domagala is a specialist in Prosthodontics, Associate Professor, and founder of Major Dental Clinics. With more than 20 years of experience, he focuses on implants, reconstructive, and esthetic dentistry, helping patients restore function, comfort, and confidence in their smiles.
Dr. Domagala holds a Certificate of Specialty in Prosthodontics and a Master of Science degree in Implant Prosthetics from Marquette University School of Dentistry. Passionate about innovation, he has advanced training in digital dentistry, including 3D design, milling, and printing technologies. His academic and research accomplishments include the Marquette Graduate Prosthodontics Scholarship, Marquette Research Day Award, and American Prosthodontics Society Award. His dental implant research was supported by the Tylman Grant and received the Tylman First Prize Award. Committed to excellence in patient care, Dr. Domagala continuously advances his expertise to provide innovative solutions and create natural-looking, functional, and lasting smiles.
“Advanced dentistry is not just about solving a complex problem. It is about understanding the whole patient, planning carefully, and creating a result that looks natural, functions well, and lasts.”
— Dr. Daniel Domagala
Advanced Education & Training
Extensive postgraduate education in advanced dentistry and implantology.
Honors & Recognition
Recognized for excellence in leadership, research, and clinical achievement.
Commitment to Excellence
Continuing education and innovation for the highest standard of care.
Patients First, Always
Building lasting relationships through trust and compassion.
ADVANCED TECHNOLOGY
Better Technology.
Better Smiles.
We invest in the most advanced technology to ensure precision, comfort, and optimal outcomes.
Digital X-Rays
High-resolution imaging with up to 90% less radiation.
Intraoral Scanners
Comfortable, precise impressions no goopy mess.
3D CBCT Imaging
Detailed 3D imaging for accurate diagnosis and planning.
In-house laboratory
Expertly crafted and placed for a natural looking smile.
Testimonials
WHAT OUR PATIENTS SAY
Ali
Patient
I had a dental emergency after falling and breaking my front tooth. Smile MKE was able to get me in right away and, thankfully, save the tooth. They even checked my insurance while I was there, so I knew exactly what I would have to pay out of pocket. Everyone was kind and reassuring, and the whole experience was much easier than I expected. I’ll definitely be back for more dental care.
Emily
Patient
What a great dental clinic. I live downtown, so being able to walk there is a huge plus, and they’re in network with my insurance. The office is beautiful with amazing views. The hygienist was excellent, and the doctor really took time to explain everything and answer my questions. I also appreciated that there was no pressure for unnecessary treatment. I’ll definitely be back.
James
Patient
I’ve always been very afraid of the dentist and put off dental care for years. When I came to Smile MKE, I had a consultation and the doctor recommended sedation to help with my anxiety. It was the best decision I could have made. I felt calm, comfortable, and well cared for throughout the visit. I’m so glad I finally found a dental office where I feel at ease. Highly recommend Smile MKE!
Sarah
Patient
My mom is going through cancer treatment and developed a toothache. Dr. Agnes Domagala was recommended to us, and we’re very grateful we went to see her. She did a very careful exam and even contacted my wife’s oncologist to make sure any dental treatment would be safe. We really appreciated the extra care, communication, and attention.